Asks JP to remember him if anything occurs to him "in regard to inheritance at corresponding or rather earlier ages". Sends JP a few examples for his "Chronometry of life". CD is sure he often met with striking facts but he disregarded them. "Deviations alone would have struck me."

Effects of different climates on breeding periods.

Thanks JP for bearing in mind his strong wish to learn any facts on inheritance at corresponding ages, and on correlation of growth.

JP’s case of teeth affected by syphilitic parents seems very curious. Would like to hear a few particulars when they meet.

Forwards a book [Horace Dobell, Lectures on the germs and vestiges of disease (1861)] and a genealogical table at the author’s request.

Sends a sentence, quoting JP, on inherited peculiarities in eye-brows. Asks whether he may use it in his chapter on inheritance [Variation, ch. 12].

Sends two [unidentified] papers on inheritance of medical malformations. Suggests that besides the inheritance of specific variations, the tendency to show variations in the same organ system (stomach, nervous, etc.) may also be inherited.

Will seek answers to CD’s questions on expression. Observing patients’ blushing. Is CD interested in the platysma during screaming under chloroform?

Thanks for Variation. Expects to be made more ashamed by his ignorance of the "influence of inheritance on the variations and mixtures of disease".

"I enclose a note from Lord Fitzwilliam about his horse with zebra-marks. The case seems as striking as I believed."

Has made a wonderful recovery [from riding accident].

Asks for information on blushing and screaming [for Expression].

Thanks for confirmation about the extent of blushing.

Passed JP’s house but did not call; and now regrets his restraint.

Asks to have observations made of a person retching violently, but ejecting nothing from stomach, in order to test relation between spasmodic contraction of orbicular muscles and tears. CD believes tears are caused by matter filling nostrils.

"I am at work on the nervous mimicry of organic disease: I have some hope that, during my work, I may fall on some facts which may be of interest to you, and you may be sure that I shall send them to you."

"Sir William Gull has just brought me the enclosed quotations from Chaucer, as illustrations of the closure of the eyes in effort. [In "The Nun’s priest’s tale" in Canterbury tales the fox tricks Chanticleer into crowing, whereupon Chanticleer closes his eyes to make the effort (and gets seized by the fox).] He begs me to send them to you.

I have lately seen a terrier who very distinctly frowns during mental excitement – not always with anger, but often, I think, with anxiety, as in expecting food."

Describes a patient’s ears with peculiar tufts of hair in places where he has never seen them before. Encloses sketch.

JP’s note [8739] suggests reversion, but that is an easy trap. Will look to the ears of "our brethren at the Zool. Gardens".

Has heard from Ashwin Conway Newman of Guy’s Hospital of a case of a child without any prepuce whose father was a renegade, uncircumcised Jew, but whose ancestors had all been Jews. Newman thinks this a good case of inheritance with reversion. JP’s letter [missing] now shows how rash such a conclusion would be.

Thanks JP for volume of his lectures [Clinical lectures and essays, ed. H. Marsh (1875)].

Mentions "vivisection question".

A letter introducing T. F. Burgers, President of the Transvaal Republic.

Thanks for Insectivorous plants.

Intrigued by the analogy between fairy-rings and annular skin diseases, e.g., herpes and psoriasis.

Encloses copy of description of an outgrown stump. Refers to letter [missing] in which CD reports on a case of amputation. Would like to check J. Simpson’s cases before thinking everything is settled.