Wilhelm Friedrich Kühne (1837–1900)

German physiologist. Studied at the University of Göttingen, 1854–6; his PhD thesis was on induced diabetes in frogs. Worked in Jena, Berlin, Paris, and Vienna. Assistant in the chemical department at Rudolph Virchow’s institute, Berlin, 1861–8. Professor of physiology, Amsterdam, 1868–71; Heidelberg, 1871–99. Worked on the physiology of metabolism and digestion, of muscle and nerves, and of protozoa, and on physiological optics. Was the first to isolate the enzyme trypsin.