Instructions for a journey to the sulphur deposits of the Valle de la Coipa.

Describes volcanic formations capping granite hills from Copiapò to Atacama [Chile]. [See South America, pp. 230–1.]

Sends CD passages from A. S. Taylor’s book [On poisons in relation to medical jurisprudence and medicine, 2d ed. (1859)], citing smallest portions of poisons that are chemically detectable. "Drosera beats the chemists hollow."

Explains discrepancies in weights and measures caused by changes since 1836 in apothecaries’ measures.

EC has found that a discrepancy in A. W. von Hofmann’s experiments with iodine solutions resulted from an error in Hofmann’s use of decimals.

Reports S. P. Woodward’s opinion of the Origin: "a very sad book, it unsettles all one’s religious principles and the worst of it is so much of it is true".

CD’s divergent series explains those anomalous plants that hover between what would otherwise be two species in a genus.

Inclined to see conifers as a sub-series of dicotyledons that developed in parallel to monocotyledons, but retained cryptogamic characters.

Mentions H. C. Watson’s view of variations.

Man has destroyed more species than he has created varieties.

Variations are centrifugal because the chances are a million to one that identity of form once lost will return.

In the human race, we find no reversion "that would lead us to confound a man with his ancestors".

Discusses dimorphism and suggests CD investigate Valeriana.

Praises CD’s views with respect to the U. S. Civil War and relations with England. Worsening relations between Britain and U. S.

Wrote a "frightful screed" about aristocracy’s being a necessary consequence of natural selection, and then burnt it.

H. W. Bates is the only man "thinking out" natural selection to any purpose. "I think I have driven Bates back to Nat. Sel. as the only way of solving his difficulties."

HWB’s mimetic butterflies.

JDH wishes he had time to do the same thing with plants.

Owen and Huxley involved in a "contemptible" squabble in the Edinburgh newspapers.

Maximovitch reports Stellaria bulbifera is a Siberian form which never ripens its seeds.

E. A. Parkes informs him there will be difficulty about the Army returns [on CD’s Query to Army surgeons, see Freeman, Works of Charles Darwin, p. 111] owing to official obstructions by Director General. [Enclosed letter from Parkes to GB says that the Director General does not think that Army surgeons could be asked to collect information systematically for CD, but perhaps some informal, voluntary arrangement could be made.]

Encloses a passage from his book, The botany of the voyage of H.M.S. "Herald" [1852–7].

Discusses possibility of publishing work on flora of Hawaiian Islands.

Discusses insects of south temperate S. America and New Zealand, especially with respect to the distribution and origin of Chilean Carabi, and has sent for a German monograph to learn about the eleven species he has found.

He refers to Chilean poverty in butterflies; scanty New Zealand insect fauna.

An analysis of south temperate insects is desirable, but the small English collections make him afraid to undertake it.

Sends CD a quotation from Plato which anticipates the Origin.

Has been enjoying CD’s paper on dimorphism in the Journal of the Linnean Society ["Two forms of Primula", Collected papers 2: 45–63]. He has found similar structures [see Forms of flowers, pp. 116, 122].

Comments on presentation copy of Orchids. Has CD studied the orchid Sobralia?

Cannot get material for hollyhock experiment.

Sends his notes on Primula sinensis.

He is experimenting on Ranunculus.

L. C. Treviranus inclined to translate Orchids, but "unfortunately" HGB has already done it. Book’s discussion of plant sexuality important for zoology as well as botany.

Origin is in press. Attaches a list of "quelques petites difficultées" encountered in his translation.

Observations on Platanthera.

Possibility of trimorphism in Mertensia.

Wife’s health improved by trip.

Heer’s collections convince JDH that Miocene vegetation was Himalayan, not American, as Heer supposed.

Zurich promises to be a good natural history school.

Review of Natural History Review in Parthenon [1 (1862): 373–5].

Suggests CD try to get Lythrum hyssopifolia from France.

Dimorphic flowers.

Differences between newly opened and older orchids.

Flowers of Spiranthes and Goodyera.

EB has had his pension disallowed; is coming to England.

Encloses maize seeds.

Has heard of a butterfly with pollinia of Platanthera stuck to it.

Comments on AG’s notes ["Dimorphism in the genitalia of flowers", Am. J. Sci. 2d ser. 34 (1862): 149–50].

"Precocious fertilisation".

Studying self-sterility, particularly in Oncidium, where abortion occurs consistently but stigma functions normally. His hybrid orchid crosses show sterility occurs capriciously. Thus it is not a "special endowment".

Disputes Asa Gray’s and Hermann Crüger’s view of rostellar germination.

Doubts absolute sterility of Catasetum.

Disappointed by results with homomorphic cowslips.

Observations on Catasetum.

Figs require insects in order to set seed.

Observes Plantago’s out-crossing mechanism.

Observations of style lengths of primroses and cowslips.