JT’s tube [of boiled infusion] dated 16 Oct was clear on 19th; on the 20th it was muddy and contained many bacteria in living movement.

Asks JT to send the tubes [of boiled infusions]. Frank Darwin will do his best. Asks for full instructions.

Sends congratulations and a teapot on the occasion of JT’s engagement.

Is pleased JT is not giving up on the spontaneous generation question. Feels strongly that subject will not be clear until it is understood how J. S. Burdon Sanderson and others succeeded in getting bacteria in infusions they had boiled for a long time.

CD has quite given up the marine theory [of Glen Roy] and has accepted glacier lakes. "Nothing makes me gnash my teeth so much as that confounded paper of mine." It is a lesson "never in science to infer one explanation is right because no other one seems possible".

Has read JT’s address ["Science and man", The Times, 2 October 1877, p. 8]. What JT says about CD honours and pleases him. JT’s short character of Faraday is beautiful.

Has observed, perhaps erroneously, that certain plants were excited to movement by a prolonged high note on the bassoon. Would now like to try a siren and asks JT to bring one from the Royal Institution.

Returns the siren; the plants "ill luck to them, are not sensitive to aerial vibrations". Is ashamed of his blunder.

Has been asked to contribute to W. K. Clifford memorial fund. Asks JT’s advice on how much the committee hopes to raise. Would like to give handsomely but feels bound "with such a lot of children, not to be extravagant".

Thanks JT for his information. Sends £50 to the W. K. Clifford memorial fund.

Sends W. K. Clifford subscription.

Has been unwell and hardly able to do anything. Has seen Andrew Clark.

Asks JT to support Albert Dicey for the Athenaeum.

CD is "as ignorant of mechanics as a pig", but glaciers have interested him greatly. Hopes to hear that JT’s experiments with ice will explain the freezing together of ice below the freezing point.

Sends correspondence between Dr Erasmus Darwin and Josiah Wedgwood I [of Etruria] on glaciers.

Also a pamphlet [Asa Gray, Natural selection not inconsistent with natural theology (1861)] containing "the best account" of the Origin.

Has been idling and enjoying the scenery.

"At dinner we were all sticking bits of ice together by their points, marvelling at the phenomenon and talking of you."

Asks JT to distribute some circulars about the work of Gustavus Hinrichs of Iowa, whom CD wishes to help.

Admires JT’s Norwich address [to Mathematics and Physics Section, BAAS meeting, Rep. BAAS 38: 1–6] and his Fortnightly Review paper on scientific discovery [7 (1867): 645–60].

Invites JT to come to Down with the Asa Grays and Hookers.

CD finds JT’s discourse "grand and most interesting" [On the scientific use of the imagination (1870)]. Flattered by what JT says about him.

He is "a rash man to say a good word for Pangenesis for it has hardly a friend among naturalists".

CD is much struck with what JT says about "pondering" and delighted by his "as if" argument.

Thinks JT’s discovery of a glycerine respirator is an interesting practical discovery. CD has been wondering about the hairs in our nostrils, but doubts that JT has explained their function, since there are hardly enough.

Will ask W. Ogle to observe hairs in nostrils of different races.

Ogle will keep JT’s suggestion in mind in observing less hairy races of man and the lower animals.

Asks JT whether he can help Ogle on a troublesome point on the colour of tissues with olfactory nerves, and the relation of colour to the absorption of odours. Does JT’s respirator deprive odorous substances of their smell?

Ogle is unacquainted with JT; would be proud and pleased to call on him. CD likes what little he has seen of him.