Admires Edward Forbes’s theory of continental extensions, but it will discourage investigation of distribution.

Mentions Oswald Heer’s proposed map of Atlantis.

Discusses extinction of plants caused by the glacial era. Migration of plants and animals during glacial period.

Encourages CL’s work [on Antiquity of man (1863)].

Comments on unfriendly reviews. Asks CL’s opinion about including a reply to reviewers in next edition of Origin.

Comments on CL’s advice not to reply directly to reviews.

Describes work on his Drosera manuscript.

Work delayed on his "larger book" [Variation].

Comments at length on the evolutionary significance of Robert McDonnell’s investigations ["On an organ in the skate", Nat. Hist. Rev. (1861): 57–60].

Discusses elevation and subsidence of Europe.