Anxious to receive letter his father promised. Shortly leaving Rome, from whence he [and William Younge] are travelling to Bologna, Venice, and Milan. Met Mr Marsh; symptoms of his illness. Has met [Anthony] Aufrere several times at Rome. Difficulties of acquiring money at Rome. Informed by Broussonet that he has been elected a member of the Paris Royal Agricultural Society. Account of their activities in Rome, including visits to churches. Usefulness of Lady Miller's letters for ease of travelling here.

Received his father's letter of 29 March [1787] and mother's of 19 March [1787], and his last letter was of 7 May [1787]. Responds to news in his parents' letters. His intended future movements in Italy. Account of his [and William Younge's] journey from Bologna to Milan, via Venice, account of their time there, Padua, Verona, Mantua, and Parma. Their movements after leaving Milan.

Received his parents' letters of 16 May, 21 May, and 28 May [1787]. Sending books home. Sorry to hear of Molly Standard's "folly & misfortune" [Smith's housekeeper; she had become pregnant]. Conduct of cousin Thomas Smith and his sister fills him with "surprise & indignation [...] shame & contempt". Has advised Mr Marsh to take a ship home to England, realising that he will never get well on land, and his father demands his return as he has spent over £600 in the last 6 months. Details of his and [William] Younge's parting of ways. "Very well pleased" with a servant he hired at Milan, though he "dresses hair badly".

During his time at Pavia met Scopoli, who having heard he intends to publish some works of Linnaeus, offered all his notes; had his suspicions about Spalanzani and Scopoli fully justified; account of Spalanzani; overlooking translation of his publication into Italian [probably his Leyden dissertation]. Time spent with the Marquis Durazzo. Suffered a slight health scare but now better.

Enjoyment of his life and studies in Edinburgh. Reassures his father that there is no danger of botany engrossing his attention too much. His enjoyment of anatomy, has undertaken the Materia Medica, will attend on an apothecary's shop in the summer. Dr [John] Hope's kind attentions. Dined with Mr Gloag, account of his family and status. Dined with Dr Hutton and Dr Black. Excesses of his fellow lodgers, [John Henry] Engelhart and Mr Lubbock. Requests black silk stockings.

Sent on 23 [July 1787]. Received his father's letter of 2 July [1787], sorry his letter of 8 June [1787] took so long in reaching Norwich. His reasons for extending his stay in Genoa. Forced to buy himself a new outfit at Genoa. Lists all the sums of money he has taken since leaving Paris. Pleasure of travelling with [William] Younge. Responds to points in his father's letter regarding his travels. Has met Mr Caffarena, who reports that England is in danger of a war from "the folly of our booby King [George III (1738-1820)]; Mr [William] Pitt [(1759-1806), prime minister 1783-1801] will be very popular for his conduct"; hopes the King will not be able to do without him. His time with the Marquis Durazzo. Dreams of his future house being a place of relaxation for his parents.

Sent 4 [August 1787]. Hot weather has set in, exceeding anything experienced in England, but not intolerable. Received his father's letter of 19 July [1787]; sorry to hear state of things at Chelsea have caused his parents so much trouble [pregnancy of Smith's housekeeper, Molly Standard]; expects to be in London by Michaelmas [29 September]. Concerned for fate of his friend Cooper, and "melancholy state" of [Robert] Batty, whose death would be the "first real misfortune" he ever felt. Glad his father has read [Jean-Jacques] Rousseau's [(1712-1778), philosopher] "Confessions"; their reputation for shock; other book recommendations. Notes on silk business and prices for his father's bales.

Hopes his father received his letter of 4 August [1787]. Kindness of Messrs Malanot and Maghit; their regard for his father. His calls on cloth merchants and investigations into silk production. Mr Malanot so excessively hospitable as to make him uneasy. Invited by de Sousa, the Portuguese ambassador, to meet all the corps diplomatique. Has met a Milanese boy who is "such a treasure" he intends to bring him back to England, and is so clever he intends to "make him earn" what he costs [François Borone]. Account of a botanical excursion he made to Mount Cenis with de Sousa and other botanists and natural philosophers. Account of his arrival in Geneva, which "swarms with English people"; so far has only met Professor Zimmerman; meeting Mr Bonnet tomorrow. After Geneva will visit the glaciers, Lausanne, Berne, Basle, and Strasbourg, before reaching Paris.

Delighted by most recent letters he received from his father, including news of [Robert] Batty's recovered health, his family's pleasant stay in Chelsea, and plan for his parents to stay for longer than first planned. His hopes for Richard [Smith's brother] and business planned for him. Pleased by plan for Francis [Smith's brother] to meet him in Paris. His chief occupation in Paris is to finish examining Tournefort's herbarium, to which he has access through Broussonet's interest, to describe all the unknown plants. Directions for Francis' arrival, including dress.

[Note by Frances Smith on reverse of letter] detailing forwarding of letter and social engagements.

Thanks for apples and his personal items. Recent dinners. His landlady "a very neat clever woman". He has decided to become a "Physician pupil" at St Bartholomew's, for fee of 21 or 25 guineas; its benefits, including not having to dissect.