Thanks for Smith's interest in [Jacob] Bigelow joining Linnean Society as FMLS; concerns over the 23 guineas required for his subscription. Examined plants from mountains around Boston, [Massachusetts], with Sir Joseph Banks and [Robert] Brown, notes on their conclusions, including: 'Scirpus bracteatus', 'Epipactis convallarioides', 'Matonia inflata', 'Hylas assyllus', 'Potomogeton tenellum', 'Orchis bracteata', 'Lycopodium lucidulum', and 'Halcus monticula'.

As yet has been unable to examine his plants with any standard herbarium, something he is keen to do to expand USA's natural history, understands [Aylmer Bourke] Lambert has Pursh's herbarium.

Death of his father necessitates his return home [to USA]. Sends plants. Seeks admission to Linnean Society; expects to be able to dedicate himself more to science on his return to England.

No longer able to visit Norwich. Sends Mrs [Lucy] Hardcastle's fungi drawings. Felt his "insignificance" when calling on Sir Joseph Banks and [Robert] Brown and finding both busy; will defer joining the Linnean Society until he has something other than zeal to recommend him; asks for botanical book recommendations.

Thanks for plants; gazed with "admiration & delight upon the New Holland plants"; frustration at not having met Smith. Waiting to for confirmation of [Jacob] Bigelow's finances before proceeding with Bigelow's admission to Linnean Society; deferring his own admission until he returns to Britain. Discusses the Linnean Society of New England: established 2 years ago; Bigelow the "life & soul of it"; its current goal to collect the "natural curiosities" of USA; Judge Davis the president; honour it would receive if Smith became Honorary Member.

Notices that Smith has admitted 'Ornithogalum [distans]' a British plans. Mrs [Lucy] Hardcastle to copy the branched 'Agaric' for Smith; she also copied 'Iris gracilis' for Smith. Observations on a fungus found in Derby Infirmary, transcribes remarks by surgeon on appearance and habitat. Requests sample of handwriting of Sir Joseph Banks.

Ship delayed in sailing [for USA]. Mrs [Lucy] Hardcastle delayed in preparing the drawings she was to send Smith; the parcel will contain dried specimen of a 'Rhizomenpha', on which Dr Forster will write in greater detail. Observations on Cornish plants: 'Ulex europans', 'Viola canina', 'Scalo pendiam', 'Statice arvensis', 'Anthyllis', 'Silene maritima'. Has the parcels for [Jacob] Bigelow and [David] Hosack.

Sends plants from New York and New Hampshire. Brief account of his journey through Nova Scotia to Boston, [Massachusetts]. Arrived back in Britain in August. Has a parcel of plants for Smith from [Jacob] Bigelow; new species of 'Orchis' nearly allied to 'O. fimbriata'; they are to write a "Flora of the Eastern States" together; preparations for the work. Observations on American plants, including: 'Viola parviflora', 'Viola clandestina', 'Claytonia spatulafolius', 'Erythronium', 'Silene'. Requests introduction to [Aylmer Bourke] Lambert so as to consult Pursh's herbarium, in Lambert's possession. Assistance received from [Robert] Brown and use of Sir Joseph Banks' library.

Hopes Smith's health is better. Sends parcel of plants from [Jacob] Bigelow. Opinion on a pamphlet on young of snakes. Sent Smith's letter of introduction to [Aylmer Bourke] Lambert. New Derbyshire habitat for 'Clavaria ardenia'.

Thanks for turkey. Glad Smith's health improved; convinced there is no diseased disorganisation in his chest but recommends living temperately and regular exercise. Prescribes Pelula Hydraggii for his headaches.

The complaint Smith mentions is a tendency towards diabetes; prescribes laudanum, and rhubarb for costiveness. Smith should eat fewer vegetables and more meat, drink water, and avoid dessert.

Thanks for turkey. Pleased Smith's complaint is reducing but his measures not energetic enough; recommends 40 drops of laudanum a day, to add carbonate of ammonia to his camomile tea and tincture of 'Gentiana', to eat as much meat as possible, and to drink Bristol water, for several years.

Thanks for turkies and buns. Comments on Smith's article on botany in the "Scotch Encyclopedia" [Rees' "Cyclopedia"], which he had previously neglected to peruse; admires his defence of Linnaeus' natural classes but considers De Jussieu's system superior. Comments on the "immense" improvement in botany since he first started studying it, citing Smith and [James] Sowerby's "English botany", which would have saved him years of labour.

[Note in Smith's hand] this letter printed in "Selection of the Correspondence of Linnaeus" vol 2 p.577.

Sends specimens of American locust and Hessian fly from Judge [Richard] Peters [(1743-1828)], president of the Agricultural Society of Philadelphia, and seven papers also from Peters on these subjects.

[Francis] Boott unexpectedly returning to England. He has invited Boott to work on his "Flora of New England"; as yet they are novices in the science and have much to gain from Smith's advice; similarities and differences of New England and European floras. State of science in USA "rapidly progressive" but not yet advanced enough to support the "luxuries of science", such as coloured engravings of American plants; he is making the experiment in his "Medical Botany", sends plates via Boott. Sends pencilled sketch of an 'Orchis grandiflora', close to 'O. fimbriata'. Corrêa is Portugeuse Minister Plenipotentiary at Washington. Requests that the plants he sent Smith for determination be reserved for his and Boott's flora; some have since been published in Elliott's; further query on the two 'Rubus'.

Professor of Physic will not oppose Smith giving lectures or using the Physic garden, and confident that if Smith's other friend exerts himself another curator of the garden will be gained in Smith's favour [in reference to Smith's campaign for Cambridge botany professorship]. Advises Smith to come in person to look over his interests. Asks if Smith is to make any alterations to "Flora Britannica" as he intends to have his bound.

Encloses paper on vegetable physiology for the Linnean Society; requests that it be returned if not suitable.

[Smith has annotated "paper returned']

Sending box of plants for Smith's opinion, numbered list of contents with his own observations, including: 'Lotus decumbens' or 'L. debilis', 'Cnicus heteroclitus' or 'C. elegans', 'Verbascum virgatum', a 'Malva', and others.

Thanks for Smith's letter; glad Smith determined 'Lotus angustifolius', which was his original name for it, has cultivated it for years. Discusses 'Cnicus heteroclitus'; small sketch in ink of root. Lists desiderata taken from "Flora Britannica" of plants he would like to cultivate.

Will assist Smith's nephew, Edward Smith, any way he can, though business currently slow. Studying 'Rubus', list of species he has found here.

Forwarded Smith's letter to Mr Napier. Pleased Smith will be at Linnean Society anniversary meeting. Hears from [Alexander] MacLeay that [Thomas] Marsham is unwell; hopes this is not a ruse to avoid payment of the money Marsham owes the Society. Smith's information about [Edward] Rudge "without a shadow of foundation".

Thanks for Smith's letter and his notice of her drawings of 'Fungi'. Hopes Smith will visit her if he comes to Derby, or [Francis] Boott if Matlock, [Derbuyshire]. Forwards further drawing of a 'Rhizomorpha' and section of the reservoir in which it was found growing by Mr Bainbrigge of the Infirmary. Apologises for not previously sending drawing.

Sends plants from [Olof] Swartz for confirmation. Thanks for Smith's remarks on his "Flora Londinensis" work. About to publish a periodical work on "exotic mosses"; requests specimens.