Introduces Mr Istria, a medical doctor interested in natural history and botany.

Toscanelli has received books sent by Smith. [Rodrigo] de Sousa [Coutinho] pleased with Smith's works and sends respects. Smith's views largely concurrent with his own on plants of uncertain classification, although disagrees on 'Cynanchum muscicapum', 'Carduus erisithales' in [Carlo] Allioni's opinion 'Carduus rivularis'. Habitat for 'Festuca flavescens'. Doubts on 'Allium nigrum', more likely to be 'Allium narcissi' or 'Allium alpinum'. Asks Smith to compare 'Androsacea lactea' with 'Androsacea septentrionalis'. Would like Smith's opinion on his naming of 'Saxifraga elongata'. Confirmation of 'Aira vallesiaca'. Has named 'Ranunculus curvatu' 'Ranunculus lacerus'. Asks for a transcript of pages from "Hortus Kewensis" on 'Primula' to assist in his work on 'Primula emarginata' and 'Saxifraga lingulata', and pages from another work. Has received specimen of 'Pilularia' and seeds of 'Cornucopiae cucullatum'. Smith elected to the Academy of Sciences. Requests rare seeds from Smith for a friend, a copy of "Flora Lapponica", and information on the new edition of "Systema Vegetabilium".

Sends his "Appendix ad Floram Pedemontanam". Thanks Smith for the "Linnean Transactions" sent to himself and [Rodrigo] de Sousa [Coutinho]. Academy of Sciences looking forward to receiving works from Smith.

Present state of affairs make correspondence difficult. [Rodrigo] de Sousa [Coutinho] anxious to receive any works by Smith that are not listed [in letter] with those he already owns, alongside Aiton's "Hotus Kewensis", Linnaeus' "Flora Lapponica", and [James] Dickson's ["Plantarum cryptogamicarum Britanniae"].

Thanks for seeds [not named] and pleased that the specimen he sent [illegible] has met with approval, the plant of which is the most "beautiful vegetable [he] has yet seen in bloom", and was sketched by Mr Bacon.

Has been collecting rare English maritime plants at Lymington, Hampshire, and Brownsea Island, Dorset; 'Inula cruthmoides', 'Ruppia maritima', 'Chironia pulchella', 'Chironia centaurium', 'Anthemis maritima', 'Beta maritima', 'Santolina maritima', 'Cheiranthus sinautus', 'Salosa kali', 'Pinguicula lusitanica', and a possible 'Schoenus longus'. Expecting 29,300 plants sent from Jamaica. Has been growing 'Sedum villosum' for three years, a "perfect perennial". Asks Smith to obtain living plants of 'Pulmonaria maritima' and 'Convolvulus soldanella', which grow on the Norfolk coast.

Thanks for introduction to Dr Duncan, who has been visiting. Details of a business transaction. Notes that Smith will receive a letter from [Christiaan Hendrik] Persoon. Encloses a recently published pamphlet, ["De vi vitali sanguini..." (1795)]. The "enigmatical sea-animal of the class of worms" from Linnaean collections that Smith sent Blumenbach is a 'Sabella' as described in [Johann Samuel] Schröter, "Einleitung in die Conchylienkenntniss nach Linne" (1783-1786).

Thanks for diploma of Linnean Society. Sends papers on botany and entomology. Introduces Brogniard.

Bust of Linnaeus erected in Jardin des Plantes. Paris Linnean Society reformed as the Société d'Histoire Naturelle de Paris, Smith made an Associate.

Thanks for "Linnean Transactions". Sends papers for publication. Natural science not neglected despite the Revolution.

Writes in reference to 'Pyrola uniflora', specimens of which he once sent to [James] Hoy of Gordon Castle and which has since been included in a work of [James] Sowerby's, but believes Sowerby has not succeeded in correctly documenting it and will send more specimens for further attention. Relates that John Mackay [(1772-1802) employed at Dickson nursery, Edinburgh] has discovered many plants in north and west Scotland overlooked by [John] Lightfoot, list sent to Sowerby along with specimens of 'Eriocaulon decangulare', Mackay to send seeds of same shortly. Recommends Mackay as a collector. Has received from Dominica seeds and drawing of plant sent as the true 'Iecacuanha' but believes it to be 'Asclepias curassavica' as does [Daniel] Rutherford, will send specimen if desired.

Has reminded [John] Mackay [(1772-1802), employed at Dickson nursery, Edinburgh] to send specimens of 'Eriocaulon decangulare'. Thinks [James] Hoy an excellent botanist. Behaviour of 'Pyrola uniflora' on island of Harris leads him to believe that [Richard] Gotobed's account is wrong. His woods plentiful with 'Satyrium repens' and 'Ophrys cordata', sending specimens of both to [James] Sowerby. Has been unable to find 'Satyrium albidum'. 'Linnaea borealis' flowering well in his botanical garden but has never found it wild, will ask [James] Beat[t]ie about it.

Sending by Mr Falconer specimen and seeds of a grass from the Cape of Good Hope, believes it to be 'Holeus saccharatus' but seeks Smith's opinion. Poor weather has prevented him from pursuing botany.

Has spent the last eight months in the 2nd Regiment militia which has prevented him from pursuing his botany interests. Glad Smith has seen 'Cycas revoluta', Smith will to determine whether the genus should with the palms or the ferns. Jokes that the "ardour in botanical pursuits is so great" he would not be surprised to hear Smith had found [Carl Peter] Thunberg's 'Disa longicornis', 'Serapias melaleuca' and 'Ixia maculata' in Britain.

Writes on introduction of Mr Este, following request for introductions in Europe.

[Smith has noted his reply on recto of folio]: sent letters of introduction to Professor Hoffmann, Göttingen; Professor Oriani, Milan; and Dr Dana, Turin.

Encloses generic description of 'Afzelia' [extant]. Studied the 'Brownea' and found they consitute a whole family; Linnaeus took the genus up from Jacquin, Jacquin's first plant different species from Loesling's, among his African plants there are 3 genera belonging to 'Brownea' family, [William] Roxburgh's 'Jonesia' and Aublet's 'Eperica' also belong to it; queries for Smith to follow up.

[Note in Smith's hand detailing his reply] will soon publish essential characters of 'Afzelia' with some other genera in a pamphlet.

Description of 'Afzelia' [in Latin, 4 pp]

Recalls Smith's surprise at her asking him to her stockbroker. Asks Smith to give description of her eye complaint to Mr Pennington, Pott the surgeon's favourite pupil.

Invites Smith to visit him on his way back from Hafod, [Cardiganshire, home of Thomas Johnes].

His friend, Dr Salt of Birmingham, has found 'Gnaphalium margaritaceum' in Longdon parish, near Lichfield, [Staffordshire], in a meadow with small stream running through it. Sent in addition to [Thomas] Butt's letter [of 17 December 1799].

Confirmation that their low expectations [regarding sale of the Linnaean fossils] were well founded: worthless chaos of the Linnaean cabinet contained only one valuable specimen; concerned that the efforts of himself and Dr Mitchell in organising it worked towards Smith's disadvantage; thought that Dr Lettsom would be a possible purchaser, and he did call at Mr King's, but did not attend the sale. Advertisement of Smith's lectures [at Guy's Hospital, London]. Balance from the sale.