Two queries on teeth: 1. Is there evidence of inherited peculiarities in milk teeth?

2. Are male incisors longer than female?

Recommends papers on Styrian Cave insects and American cave animals.

Thanks for information on inheritance of mental peculiarities in cats.

Discusses deduction from bill for medicine.

"I shall not be in London on Monday, but I have written to my Brother to ask him to aid you"

Asks for information about JC’s essay, "On the relation of the domesticated animals to civilisation" [read at BAAS meeting 1859].

Obliged for the Theophrastus. Will return it.

Instructions on paying a bill.

Seeks investment advice.

Promises to send coral specimens.

Thanks TCE for telling him of his crossed pigs. When they are grown, he would like to know whether they resemble each other.

Doubts the half-bred Gallus sonnerati will be productive, though he was assured many years ago that such a fertile half-breed once occurred.

Arrangements to dine at JDH’s club.

Thanks THH for the delightful evening he gave Frank [Darwin].

Regrets he does not have pedigree of CL’s "pretty pony", but assures him information was very useful, "more especially as it confirms what I heard from Norway & did not know whether fully to believe".

CD asks if he can call tomorrow (Friday) at 9: 30, and offers to come on Saturday if that would suit CL better.

Thanks for facts on inheritance. May be used if CD corrects 3d ed. [2d ed.] of Variation.

CD has signed the enclosed with great pleasure.

Last page of a letter with a five-line P.S. concerning pen-holders.

Discusses exchange of photographs with Édouard Claparède, "for whom I feel the highest respect".

"When a man has laboured hard in science & has proved that he is capable of original research, he may [some]times indulge in speculation [&] the public will indulge him. But even in this case it is a common error to speculate too largely, for speculation is far easier than observation or experiments . . ."