Beagle is again in Brazil because of need to check on "singular disagreements in the Longitudes".

Pleased by Sedgwick’s praise.

Happily home, he sends thanks to his "first Lord of the Admiralty". Will visit Maer in two or three weeks.

CD describes his happy home-coming. Finds his family and Shrewsbury unchanged.

Declines invitation to dine at Downing College because of influenza.

Questions on breeding and habits.

Declines Ray Club dinner; too busy with Zoology.

Thanks JSH for presenting his work to Cambridge Philosophical Society.

Asks him to get an answer from W. H. Miller on specimen of crystallised mineral.

FitzRoy is hard at work on his book [Narrative, vol. 2].

CD’s health is improved.

Describes his visit to zoo.

Gives news of E. A. Darwin and Harriet Martineau.

Thanks for ham and corrections in spelling. Gives account of his social activities in past week.

Recounts dinner at Erasmus’ house with Harriet Martineau and others, and a visit to Cambridge to stay with Henslow and meet old friends again.

Would like to attend a lecture by JFR on "geography of plants with relation to the Himalayas".

"A grand battle" at the Geological Society between Sedgwick and G. B. Greenough.

Sends RO a box of fossils from William Darwin Fox, from the Isle of Wight.

CD informs AS of the position of the Council of the Geological Society on recommending J. B. Jukes for a geological survey of Newfoundland. Feels Jukes’s application would have best chance of success if Sedgwick, his Professor at Cambridge, wrote a letter.

Questions on breeding of plants: variation in established versus new varieties; predominance of wild species and old varieties when crossed with newer forms; predominance of males versus females; correlations between ease of hybridisation and tendency to vary and undergo cultivation; reversion; correlations between hybridisation and geographic distribution.

In WH’s Amaryllidaceae [1837], does he intend to say crossing is inimical to fertility?

[Sent via J. S. Henslow; note to amanuensis Syms Covington.]

CD is led to believe there are no true permanently inbreeding, sexually reproducing beings. Thanks for replies to breeding questions.

Asks for clarification of Hippeastrum crosses: is selfing or crossing with individual of same species intended and was increased fertility due to constitution of foreign parent or due to the pollen coming from another plant? Has WH known any hybrid or mongrel to revert or to vary in a manner unlikely to be effect of soil?

Sends Journal of researches.

Questions about his college bills.

Describes the living conditions he will have on the Beagle.

The outfitting of the Beagle progresses.

CD has been dining out more than he wishes. He has met W. S. Harris of "Electricity" fame.

His fears and hopes about seasickness.

A new continent has been discovered "somewhere far South". "Perhaps we may be sent in search."

CD’s enjoyment of the beauty of the tropics is worth all the misery of seasickness. His mail gave him great pleasure. For two weeks he will visit a large estate in the country, and on return live at Botofogo for some weeks, collecting and learning to know the tropics.

His trip to the interior was full of interest, but exhausting physically. Expects to stay at least a fortnight at Botofogo, because the Beagle returns to Bahia to correct a difference in the longitude measurements. Writes of his companions, of FitzRoy, and of his journal – which he has sent home.

Lists letters received and those sent; comments on family happenings.

The Beagle is back [from Bahia]; two sailors and "little [Charles] Musters" died of fever. In 14 days they sail for Montevideo, then to Rio Negro, then on to where no man is known to have been before.

Sailing next day to Montevideo. He has taken many hitherto undescribed animals. Describes the glories of the Brazilian forest.

Mentions his concern over the Reform Bill.