Pleased to receive letter from Smith. Smith's friend, Miss Colombine, situated in a worthy, respectable family, the Brigstockes; her misfortunes to be lamented. [Thomas] Johnes and [Mariamne] Johnes going on well. Smith must have heard much of 'Calx muriata' of Dr [Thomas] Beddoes [(1760-1808), chemist and physician]; he does not entirely subscribe to all he says of it.