His last letter to his mother, of 22 January 1787. His [and William Younge's] journey from Pisa to Rome, via Florence. Account of their time in Florence, where they were "quite in raptures"; art; the sepulchre of the Medicis; spent afternoons with Abbé Fontana. Stopped in Sienne to visit Dr Mascagni; his work on the lymphatic system. Their entrance into Rome; lodging in part of a house hired by Duke of Gloucester [Prince William Henry (1764-1805)]; compares St Peter's with St Paul's [Cathedral, London]; their itinerary.

Has learned all the particulars about Spalanzani, who "proves to be a great villain", having stolen items from the Emperor's museum and blamed Scopoli; further details of legal proceedings; many of his experiments found false; his father to inform relevant people.

Praises Smith's thesis ["Disputatio Inauguralis quaedam de Generatione complectens"]. Discusses the subject further including apparent suggestions for experiments with chickens and speculation on hereditary traits. Asks Smith to use all his energies in acquiring the "hidden treasures" of [Charles] Plumier's [(1646-1704) French botanist] collections in Paris. Asks Smith to buy any works by [Lorenzo] Bellini [(1643-1704) Italian physician and anatomist] Smith comes across. Possible incorrect classification of 'Clypeola maritima L' into 'Alyssum siculum' and 'Alyssum maritimum'. Asks for second part of [Giovanni Antonio] Scopoli's "Entomology"; [Louis] Gerard's "Flora Gallo-provincialis" and new edition of [Antoine-Joseph Dezallier] D'argenville's "Conchologie". Relates various upcoming periodicals with warning they all precede Smith's. Believes Smith will correct Linnaeus with more temperance than [Lazzaro] Spallanzani or Barrington, criticises Spallanzani's "wretched unnecessary trash". Pleased with books received from Smith but wishes [Sébastien] Vaillant had more figures in ["Botanicon Parisiense"]. Sir Thomas Cullum, Laurence and Priest have abandoned study of botany. Cullum and others in Suffolk want to establish a society to support wives and orphans of physicans, apothecaries and surgeons, Gwyn dismisses it as "relieving the parishes [of] their charges & taking away every spur to frugality and industry". Reports a favourable winter.

Hopes Smith will visit this country when he travels in Europe; received his letters of 22 June 1785 and 11 November 1785. Details of back numbers of "Proceedings of the Royal Society of Uppsala" and order by [Thomas] Pennant; contents of new volume; other new European publications. Requests anatomical writings of [William Cumberland] Cruikshank [(1745-1800), anatomist] and handbooks of [John] Hunter [(1728-1793), surgeon and anatomist]. Condemns rumours started by [Carl] Thunberg regarding sale price of Linnaean collections.