Asks CD to have stereotype plates made of new edition of Origin [5th English], if type still standing, though Appleton will reset type if necessary. Warns there is smaller audience in the U. S. for "good scientific books".

Appleton would also like plates made of new book [Descent] when possible.

Gives account of inherited blindness in a family,

and observations contravening CD’s view in Variation that sheep and other domestic animals never run wild.