Disappointed Roscoe is not visiting Holkham, [Norfolk, home of Thomas William Coke] this spring on account of his rheumatism, but as it is "unusually prevalent" lately confident that he will find the relief others have and is determined for Roscoe to visit him this year. No recollection of the picture Roscoe spoke of in his previous letter [of 27 February] but offers identification advice. Has not received Roscoe's review of [George] Canning's [(1770-1827), politician] speeches. He has written three hymns for a new collection being made at Norwich. Preparing for his London visit in April. Comments on his wife's handwriting.

Sends Roscoe a "song" of nonsense, "The New Doctors", he wrote to amuse his wife and epigram on pleasures of Holkham [both on verso of second folio].

Encourages Roscoe and Mrs Roscoe to visit Holkham, [Norfolk, home of Thomas William Coke] this autumn. Thanks for Roscoe recommending his Cambridge candidature [for botany professorship] to Professor [William] Smyth [(1765-1849), historian]; lists his many "warm & weighty friends", including: the Vice-Chancellor, the Bishop of Bristol [William Mansel], the Masters of Caius [Martin Davy], Downing [William Frere (1775-1836)], and Pembroke [Joseph Turner (1747-1828)], the Provost of King's [Humphrey Sumner], and others.

Professor [Thomas] Martyn has offered to resign whenever best suited; details of the three part position and plan for securing the professorship. Asks Roscoe to recommend him to the Duke of Gloucester [Prince William Frederick (1776-1834), chancellor of Cambridge University], hopes that he will act in favour of "whiggism & science, against mere old-fashioned espirit de corps". There are no legal obstacles or subscriptions against him but fears the Rutland interest or the Bishop of Ely [Bowyer Sparke (1759-1836)] being used against him. Coke is obtaining interests of Duke of Bedford and Lord Hardwicke; asks Roscoe to gain support of [Thomas] Creevey [(1768-1838), politician]. Recommends his biography of [José Celestino Bruno] Mutis [(1732-1808), botanist] in [Abraham] Rees' "Cyclopedia".