Since his last letter has been "seized with a paroxysm of gout in both hands and feet". Sends specimen of a "stranger", annotated in the margin by Smith 'Rubus'. Refers to the drawing of a fish he sent in his last letter, believing it to be the "15 spined stickleback figured by Pennant" but believes other aspects of it make it of the genus 'Syngnathus". Wishes Smith luck with the "English British Flora". Sends another specimen, Smith has annotated above 'Sagina procumbens'.

Sends collection of plants from the [Liverpool] Botanic Garden for use in Smith's lectures, and a small collection of duplicate 'Scitamineae' plants from [Nathaniel] Wallich, which have also been sent to Sir Joseph Banks, [Aylmer Bourke] Lambert, and [Edward] Rudge; includes 'Hedychium' and 'Roscoea'. He has been studying the former and with help of Smith's "Cyclopedia" article has made twelve distinct species, of which he will shortly send an account. Discusses Wallich's plants, some of which were unnamed, and from which he has identified four new species of 'Roscoea'. Glad Smith and Lady [Pleasance] Smith are to visit albeit for a short time, and will endeavour to make Smith's new appointment deserving of his acceptance [Professor of Botany at the Liverpool Royal Institution].

Thinks his son, Edmund, is the best appointment for headmaster of Westminster School. Believes that the discontent in the country is the fault of "itinerants who [...] poison the minds of everyone" by teaching them to think "they are denied every comfort". Uncertain what has been done at Manchester but the Attorney General confident he will prove at the trials that the magistrates and yeomanry deserved praise, not censure, in defending themselves [at Peterloo Massacre of 16 August 1819 cavalry charged into a large crowd demanding parliamentary reform, killing fifteen]. A meeting of radicals presided over by [Thomas Jonathan] Wooler [(1786-1853), journalist and radical] to be held on Monday, with the Whigs calling for another meeting the following day. Not surprised by Smith's account of the Russian train with the Archdukes. One of Goodenough's young male servants died of an inflammation thirty hours after drinking cold water when hot; his father lives with Colonel Woodhouse at Witten Hall, Norfolk.

Apologises that if in calling on Smith he intruded on his time. Sends specimen of 'Erineum acerinum' in earlier state than Smith currently has it; observations. Offers Smith use of his manuscript, in which he intends to give at least a figure for one species of every genus of fungi. Suggests alteration to [Christiaan Hendrik] Persoon's character of 'Erineum acerinum'.

["Spec. 21" written in pencil at top of verso of first folio]

Concerned to hear of Smith's indisposition; it has been agreed he appears tonight as Smith's substitute, though on a general topic and not botany; will inform the audience Smith hopes to lecture on Monday.