Introduces Jean Rasovi, a doctor and surgeon from Parma who is coming to England to learn about new medicine developments, he translated the work of Dr Brown of Edinburgh into Italian. Has heard that the new colony in Sierra Leone is struggling to establish itself and may break up, [Luigi] Borone is anxious about not having heard any news of his son [François Borone] who is there [with Adam Afzelius].

Oriani writes: Grief of Luigi Borone and family at death of his son François, received the news from Smith's letter of 10 February. Borone grateful to [John] Sibthorp, the Consul and other Englishmen who ensured his proper burial. Luigi Borone leaves François's herbarium to Smith and asks him to sell the rest of his London belongings, find out the whereabouts of his savings, and send on the money.

Borone writes: Intense grief at death of his son, asks for a copy of Smith's portrait of him.