Replies to Roscoe's letter of 18 November. Recovered from the most obstinate bowel complaint he has ever had, which confined him for three weeks. His hard work on [Abraham Rees'] "Cyclopedia", which is now coming to a close, prevents him from saying much on the "sad loss" of the Princess [Charlotte (1796-1817), only child of the Prince Regent]; wonders at possibility of a subscription for a national memorial, as with Waterloo subscription, with a school attached.

Congratulates Roscoe on opening of the Liverpool [Royal] Institution; anxious to see Roscoe's lecture in print; he and Mr Valpy do not know of anyone for the [Classical] tutor. Depending on his engagements accepts Roscoe's proposal [for Smith to lecture on botany]. Coke family "much shocked" by the sudden death of Lady [Elizabeth] Albemarle [(d 1815), first wife of William Charles Keppel, 4th Earl of Albemarle (1772-1849)] at Holkham, [Norfolk, home of Thomas William Coke], from a miscarriage. Glad that Franklin's letters have been published.