Is pleased that AdeC is interested in the Primula case ["Dimorphic condition of Primula", Collected papers 2: 45–63]. Is pursuing analogous experiments on other plants and on seedlings raised from the unions.

CD’s "large work" progresses slowly owing to ill health and his work on Orchids.

CD is not surprised that AdeC is unwilling to admit natural selection – "the subject hardly admits of direct proof or evidence. It will be believed in only by those who think that it connects & partly explains several large classes of facts".

Hopes AdeC will publish on Quercus

and rejoices that he intends to return to the study of geographical distribution. No one can claim to have read AdeC’s truly great work on that subject [Géographie botanique (1855)] with more care than CD.