Acknowledges CD’s letter about alpine entomology of Tierra del Fuego; discusses geographical distribution; urges CD to make a chart of vegetable and geological distribution of insects. Advises him on species to collect and assures him of all assistance in describing his captures on his return.

Tells of founding of Entomological Society, and enrolls CD.

News of J. F. Stephens’ lawsuit and continuation of his Illustrations of British entomology [1827–46]. Praises general state of zoological science in England.

News of family and friends: W. D. Fox will marry in the spring; private theatricals at Eaton house-party.

Writes on CD’s 25th birthday.

Points out "errors in orthography" in his journal.

News of family and friends, visits, and other social events.

They learn from a garbled report in the Times that CD’s specimens have arrived in Cambridge.

William Clift, at Royal College of Surgeons, delighted by CD’s letter about the bones that were sent to Plymouth.

Strange coincidence that Royal College of Surgeons has the front portion and CD has sent home the remainder of a skull, of which a drawing can now be completed.

Other news of family and friends.

A letter full of news of Cambridge and friends: the BAAS meeting at Cambridge; charges of corruption in the University; the Cambridge petition on behalf of Dissenters.

Describes Patagonia and its inhabitants.

Writes of his pleasure in geology.

Predicts that Falklands will become an "important halting place". Outlines Beagle’s future itinerary.

Writes a cordial letter with family and local news. Hopes CD will see his two sons in India.

P.S. by Catherine Darwin says no letter was written this month as all is well at home.

Responds to CD’s queries: the bones were received from Mr Keen and shipped to Henslow; expects another collection which he will forward.

Adds news that has arrived at Buenos Aires since CD left.

News of family and friends.

In the past six months he has done much geology and natural history. His geological pursuits are a source of high pleasure. Has lately determined to work chiefly on corals.

Spent three weeks going up the Santa Cruz with a party; they ran out of provisions 20 miles from the Cordilleras. Winter at present prevents his doing much natural history.

CD’s cargo is safe; the fossils have been sent to William Clift.

JSH asks for dried plants (those sent were all of greatest interest).

Sends news of Cambridge and mutual friends.

Thanks CD for letter of 5 April and specimens; did not know the Falklands and Patagonia were so interesting geologically.

Will answer CD’s queries about S. Brazil in another letter. Names Friedrich Sellow, A. Saint-Hilaire, and Andrew Mathews as naturalists who travelled there. Directs CD to Alexander Caldcleugh in Santiago.

Thanks for her letter of March, which gave him his first explanation of the interest in the [Megatherium] head he had sent.

Wants E. A. Darwin to tell William Clift not to remove numbers or markers on any specimens. The British Museum has first claim on any of his specimens; CD cannot at present say where any should go.

Gives a map of part of Chile between Santiago and San Fernando. Suggests places and people that CD might profitably visit [en route].

Recounts his trip [from Valparaiso] to Santiago. His meeting with Claude Gay, Thomas Sutcliffe, and others. Geology of tour uninteresting.

News of family and friends.

Word that William Clift thinks CD’s latest fossils are of much value.

Heights of various places in Chile.

No summary available.

Became ill two weeks before on his return from Santiago after an interesting trip and some geology – though snow kept him out of the Andes. FitzRoy has had to sell the schooner; he was discouraged by the Admiralty, and the expense was too much for him to bear personally.

Family and local news. Tom Eyton will marry. Tells of the great fire of the Houses of Parliament.