Louis Agassiz is going on a voyage to the Falklands, and BJS wonders whether it is worth while telling him of the Gallegos fossil bed so that he can investigate.

Suggests BJS write to Louis Agassiz about his [fossil mammal?] specimens but doubts that he will have time to do the work. Regrets they were ignored at the Royal College of Surgeons; thinks Owen neglected many things because he was overworked.

Privately advises CD against having anything to do with W. P. Snow, whose personality and past conduct on a mission vessel were very bad.

Reports on the successes of the missionaries on the Beagle Channel [Tierra del Fuego].