Asks JP to remember him if anything occurs to him "in regard to inheritance at corresponding or rather earlier ages". Sends JP a few examples for his "Chronometry of life". CD is sure he often met with striking facts but he disregarded them. "Deviations alone would have struck me."

Effects of different climates on breeding periods.

Thanks JP for bearing in mind his strong wish to learn any facts on inheritance at corresponding ages, and on correlation of growth.

JP’s case of teeth affected by syphilitic parents seems very curious. Would like to hear a few particulars when they meet.

Asks to have observations made of a person retching violently, but ejecting nothing from stomach, in order to test relation between spasmodic contraction of orbicular muscles and tears. CD believes tears are caused by matter filling nostrils.

Has heard from Ashwin Conway Newman of Guy’s Hospital of a case of a child without any prepuce whose father was a renegade, uncircumcised Jew, but whose ancestors had all been Jews. Newman thinks this a good case of inheritance with reversion. JP’s letter [missing] now shows how rash such a conclusion would be.

Surprising thought that diseases of plants should illustrate human pathology.

Will recommend A. B. Frank’s article in a German encyclopedia, on diseases of plants, to Francis Darwin.

Gives JP a good case of regeneration in plants – the radicle of the common bean. That plants have little power of regeneration is not difficult to understand by anyone who believes in Pangenesis, "if such a man exists … There is reason to think that my imaginary gemmules have small power of passing from cell to cell."

Refers to early experiments in which he tried to produce galls in plants by injecting poisons.