Reports long preparation of work on how species and varieties differ. Agreement with Wallace’s conclusions as reported in Annals and Magazine of Natural History and in his letter to CD of 10 0ct [1856]. On distinction between domestic varieties and those in "a state of nature".

On mating of jaguars and leopards, the breeding of poultry, pigeons, etc.

Requests help for his experimenting on means of distribution of organic beings on oceanic islands.

Refers to CD’s letter of "May last". ARW’s views on order of succession of species are in accordance with CD’s.

Disappointed that his paper ["On the law which has regulated the introduction of new species", Ann. & Mag. Nat. Hist. 2d ser. 16 (1855): 184–96] elicited no discussion; now ARW is trying to prove it. Paper merely states the theory.

On black jaguars breeding inter se: ARW has never heard of a parti-coloured one.

Comments on agreement of their respective views on distribution.

Reference to differences on subsidence.

Reports on progress of his work and praises ARW’s investigations.