Reassures Macleay he is not "indifferent" to the "sad event" of his departure [to New South Wales, Australia]; he feels the strongest regret. Delayed replying to Macleay's news until he had heard from [Robert] Brown but still waiting; thinks it not suited to his "retired manners" but if he undertakes it "with heart & good will" he would be the best candidate, and would not have asked him if he did not think it did Brown honour, the Bishop [of Carlisle, Samuel Goodenough] "sometimes singular in ideas".

Third volume of his "English Flora" must be finished before he comes to London, which keeps him very busy; his "correspond[en]ts have no mercy". Feels the loss of a "real friend" in Macleay.

Confesses he is "not a man of compliments", but Macleay's "wide removal, as it were, to another world [...] seems to excuse & indeed require an opening of heart between us"; pays tribute to their 31-year friendship; urges Macleay to look out for his health, citing recent death of "a most invaluable" nephew of his in India. Hopes to be in London in time to see Macleay, will be giving his first lecture at the London Institution on 2 May [1825], and until then engaged with finishing third volume of his "English Flora".

Recommended David Don [(1799-1841), botanist] to [George] Hibbert [for curator of Jamaica botanic garden]. Will be happy to see [James] Bicheno as new Linnean Society Secretary, though would have been equally pleased with [Edward] Barnard. Delighted with Macleay's son's "most excell[en]t & learned papers".