Comments on note from Charles Kingsley saying CD’s theory is not opposed to a high conception of the Deity.

Mentions negative views of Origin of Sedgwick, John Crawfurd, Roderick Murchison, John Phillips, and Joseph Prestwich.

Encloses a letter from FitzRoy to the Times.

Mentions letter from W. B. Carpenter accepting single progenitor for major animal classes.

Speculates about Richard Owen’s opinion.

Mentions English scientists who support mutability of species.

Asks QdeB whether he could help locate a French translator and publisher.

Discuss CL’s suggestions for revisions to the chapter on the geological record [Origin, ch. 9].

Henry Holland’s reaction to the book.

Comments on CL’s work on flint tools of early men.

Describes at length a conversation with Owen concerning Origin. Notes "that at bottom he goes immense way with us", but emphasises Owen’s unfriendly manner. Remarks that Owen accepted a relationship between bears and whales. "By Jove I believe he thinks a sort of Bear was the grandpapa of Whales!"

Has heard Herschel considered his book "the law of higgledy-piggledy".

Acknowledges contribution to Down Coal and Clothing Club.

Urges appointment of Edward Blyth as naturalist on an expedition to China.

Comments on Hooker’s introductory essay [in Flora Tasmaniae].

Cites C. V. Naudin’s article ["Considérations philosophiques sur l’espèce et la variété", Rev. Hortic. 4th ser. 1 (1852): 102–9].

Mentions letter from William Jardine criticising discussion of the Galapagos in the Origin.

Mentions William Clift ["Report in regard to the fossil bones found in New Holland", Edinburgh New Philos. J. 10 (1830–1): 394–6].

Discusses relations between fossil and living types.

Discusses Hooker’s introductory essay [in Flora Tasmaniae]. Criticises Hooker’s views on flora of rising and sinking islands.

Encloses letter concerning Edward Blyth’s application for a position with the China expedition.

Mentions reviews of the Origin. Guesses that Huxley wrote the Times review.

Alludes to discussion of relations between fossil and modern types [in Principles of geology 3: 144].

Discusses destruction of tropical forms in the glacial period.

Mentions letter from Dana concerning Dana’s illness.