Attacks the doctrine of "heterogeny" (spontaneous generation during each geological period) as completely lacking in evidence.

Defends natural selection as connecting large classes of facts in natural history. That certain forms have not changed since remote epochs is not an objection of any force.

Has finished vol. 1 [of Naturalist on the river Amazons]. CD praises book as "best ever published in England".

The review in the Athenæum was cold, as always, and insolent.

Describes a letter he has written to the Athenæum in which he mentions CL’s views on species modification ["Doctrine of heterogeny", Collected papers 2: 78–80].

Comments on criticism of Lyell’s book [Antiquity] by Falconer and others.

Mentions his eczema.

Invites the Lyells to visit.