CD is asked to testify before a Royal Commission on experiments on living animals.

Encloses an invitation to give evidence to Vivisection Commission. Satisfied with way things were going, but E. E. Klein’s evidence that he is utterly indifferent to pain of animals has done great mischief.

Arrangements for CD’s appearance before Vivisection Commission.

Outlines a memoir he will give at the Anthropological Society in which he differs theoretically with Pangenesis.

Personal news – is unwell.

Mentions "Twin-papers" ["Short notes on heredity, etc., in twins", J. Anthropol. Inst. 5 (1876): 324–9] sent by Galton.

Sends a proof of his "Theory of heredity" from the Contemporary Review [27 (1875): 80–95; revised in J. Anthropol. Inst. 5 (1876): 329–48]. Welcomes CD’s help and criticism.

Composition of "Droserin" [see 10015].

Thanks CD for Climbing plants and Insectivorous plants.

Discusses his research on phylogeny. Results described in "Die Gastrula und die Eifurchung der Tiere" [Jena. Z. Naturw. 9 (1875): 402–508].

Describes newly discovered coral.

Thanks for Climbing plants [2d ed.].

Is reading proofs [of Geographical distribution (1876)].

Thanks for 2d edition of Climbing plants and for CD’s recognition of HdeV’s two essays on the subject [Climbing plants, pp. v–vi, 9 n., 22, 160]. Cause of spiral growth of tendrils.

Sends successful graft-hybrid of red and white carrot.

CD should correct passage in Variation explaining deformation of sternum in fowls [Variation, 2d ed., 1: 287–8].

Chapter in Variation on Pangenesis is admirable.

Responds to suggestions and criticisms CD made to "theory of heredity" [see 10245].

Discusses his ambitions.

Writes of rats that gnaw through lead pipes to find water.

Apologises for troubling CD to look for his lost MS.

Gives an example of the power of reasoning shown by dogs.

Has CD ever come across Dischidia rafflesiana?

Has extracted a highly deliquescent substance from digestive secretion of insectivorous plants.

Hopes to continue study of climbing plants next summer and to observe facts mentioned in CD’s letter.

Report on sales of Origin, Insectivorous plants, and Climbing plants.

Queries concerned with his translation of Insectivorous plants, which has been delayed by illness but is now two-thirds done.