CD describes first observation of gyratory motion of tendrils: explains its adaptive function is to find objects to hold on to.

Describes experiments on rotation of tendrils and shoots.

Requests tendril-bearing plants.

Differences between tendrils derived from leaves and those derived from branches.

CD on Asa Gray’s attitude on the Civil War.

Asa Gray writes as if Civil War were a holy war.

J. E. Renan on Jesus [Vie de Jésus (1863)].

Literature on tendrils of Cucurbita is contradictory.

Tendril plants received.

Has just completed large crossing experiment with Lythrum.

Doubts Decaisne’s report of larkspur self-fertilisation.

Enthusiastically observes climbing plants. Needs to know how novel his observations are. Finds R. J. H. Dutrochet has made similar observations, so he has wasted some time. [See Climbing plants, p. 1 n.]

CD’s illness: he is vomiting "vegetable" cells.

Dutrochet has published the best of CD’s observations on tendrils [see Climbing plants, p. 1 n.].

Lyell has found Joshua Trimmer’s Arctic shells on Moel Tryfan.

Admits, at last, that New Zealand must have been connected to some continent, but not Australia.

Climbing plants: asks for more plants.

Condolences on death of JDH’s daughter.

Has a letter from Haast on the spreading of European plants.

Pleased with JDH’s account of his French tour.

Doctor Brinton, recommended by Busk, does not believe CD’s brain or heart affected. Feels he is going steadily downhill. If so, hopes his life will be short.

Sends Haast’s letter.

Sends Haast’s report; JDH may use any and all of the details in the letter.

Asks identity of a reviewer of Lyell’s Antiquity of man [Edinburgh Rev. 118 (1863): 254–302].

CD has a Wedgwood vase of his father’s for JDH.

Tendril-bearing plants seem to CD "higher" organised with respect to adaptive sensibility than lower animals.

Wishes to encourage John Scott.

Death of JDH’s daughter makes CD cry over his own dead daughter Annie.

Sedgwick’s scientific merit.

On Wedgwood vases for JDH.

Willy Hooker’s scarlet fever.

His bad health continues.

Thirty-two plants have come up from the earth attached to partridge’s foot.

Origin to be published in Italian.

Owen was wrong: Origin will not be forgotten in ten years.

Critical of ARW's understanding of the economy of nature.

ARW listed along with Hooker, Huxley, Lubbock and Bates as the "only honest downright "flat-footed" men in all England!!!".