Thanks for invitation [to stay with GR at Oxford], but his poor state of health requires him to stay in private lodgings.

CD’s plans are uncertain because of his daughter’s [Henrietta Darwin] fever.

If GR would kindly reserve rooms for CD near college, CD will write before the meeting [of British Association at Oxford] if he is prevented from coming.

Agrees with GR’s remarks on Asa Gray’s pamphlet.

New edition of Origin to appear immediately.

Fact of clubbed fingernails in cyanosis quite new to CD. Asks for information.

Thanks for explanation of cyanosis and clubbed nails.

Hopes GR will work out point about mucus tubes.

Thanks for answers to CD’s questions; would appreciate any new information on similarity of moths of distinct races.

CD has been "atrociously abused by religious countrymen, but it does not hurt except when it comes from an old friend like Prof. Owen".

Wishes French translator of Origin had known more natural history.

Has received [C. L.?] Brehm’s work [unspecified]. Will return it in two or three weeks.

Asks TCE to verify whether otter-hounds have more skin between their toes than other hounds. Also interested in cases of infertile matings between normally fertile individuals.

Sends observations he made on Fungia during Beagle voyage. Asks CS to make corrections in style or names of parts as he sees fit.

Had hoped to call, but cannot do so comfortably, so will HBJ call on CD instead, for a consultation?

CD has heard from the Treasury; they will pay the account [for the Zoology] as soon as Smith, Elder & Co. like.

Asks JP to remember him if anything occurs to him "in regard to inheritance at corresponding or rather earlier ages". Sends JP a few examples for his "Chronometry of life". CD is sure he often met with striking facts but he disregarded them. "Deviations alone would have struck me."

Effects of different climates on breeding periods.

Asks ADB to perform experiment on colour perception in bower-bird.

Asks for rabbit specimens.

Defers visit [to Kew] because of ill health.

Sends contribution of £5 to Settle Cave Exploration Fund.

Asks to have observations made of a person retching violently, but ejecting nothing from stomach, in order to test relation between spasmodic contraction of orbicular muscles and tears. CD believes tears are caused by matter filling nostrils.

Introduces E. L. Youmans to correspondent. Youmans is seeking small monographs by the most competent English authors [for his International Scientific Series].

Asks WWB to send 8 grains of acetate of strychnine by post.

[An autograph.] "With Mr Darwin’s compliments."

Thanks WM for his letter. CD does not think WM’s principle of [up-tending and down-tending] lines explains the cases of expression of emotions referred to, and, even if it did, the problem would remain as to why the lines should express what WM believes they do.

Arranges a visit to CL.