Forwards a book [Horace Dobell, Lectures on the germs and vestiges of disease (1861)] and a genealogical table at the author’s request.

Sends two [unidentified] papers on inheritance of medical malformations. Suggests that besides the inheritance of specific variations, the tendency to show variations in the same organ system (stomach, nervous, etc.) may also be inherited.

Will seek answers to CD’s questions on expression. Observing patients’ blushing. Is CD interested in the platysma during screaming under chloroform?

Thanks for Variation. Expects to be made more ashamed by his ignorance of the "influence of inheritance on the variations and mixtures of disease".

Describes a patient’s ears with peculiar tufts of hair in places where he has never seen them before. Encloses sketch.

A letter introducing T. F. Burgers, President of the Transvaal Republic.

Thanks for Insectivorous plants.

Intrigued by the analogy between fairy-rings and annular skin diseases, e.g., herpes and psoriasis.

Encloses copy of description of an outgrown stump. Refers to letter [missing] in which CD reports on a case of amputation. Would like to check J. Simpson’s cases before thinking everything is settled.

Instructs CD that his son [William] should take a holiday following his concussion.

Thanks JP for his kindness, but unfortunately the [unspecified] case is of no use to him.

Regrets that he cannot send the promised volume [Biographie médicale, 7 vols, 1820–5, biographical appendix to Dictionaire des sciences medicales]. Offers to have his son make an abstract of the biography [of Erasmus Darwin].

Thanks for Erasmus Darwin. It is a rare life and an unmatched illustration of the transmission of intellectual strength.

Thanks CD for his note and his new book [Movement in plants].

Makes him feel "we must go beyond plants for a really elemental pathology".

Wishes he knew enough about crystals to work at them.

Asks CD to lunch to meet the Prince of Wales.