Has been in bad health and has just read HWB’s MS in the last two days. Praises the book; assured it will be successful. Offers to write to Murray. Hooker interested in conclusions on colour.

Encloses note from Murray, hoping it will be satisfactory. Murray is ready to see as much of MS as possible. Murray is considered honest but may be cautious, since HWB’s name is unknown to the public.

Writes that [Murray’s] terms are very favourable; has never heard of such terms offered for a first work. HWB can depend on fact that Murray is pleased with it [The naturalist on the river Amazons].

Thanks for information on domestic animals of Indians.

Glad Murray thinks well of MS of The naturalist on the river Amazons.

CD working on proofs of Orchids.

Invitation to visit; Hooker will be present. Gives directions to Down. Also plans to invite John Lubbock over for an evening.

Thanks for letter and "valuable" extracts.

If S. American Carabi differ more from other species than do those from other distant locations (e.g., Siberia, Europe, etc.), CD agrees that difference would be too great to have occurred in the recent glacial age; CD also rejects independent origin. Plants seem to migrate more readily than animals. HWB should not underrate length of glacial period; CD also believes they will be driven to an older glacial period.

Sorry about news of British Museum – hopeless to contend against anyone supported by Owen.

CD dearly wishes HWB could find a situation in which he could give time to science.

Referring to conversation with Lyell, CD is certain that there was a Miocene glacial period.

Compliments HWB on the mimetic display at the British Museum. Those at the Museum readily accepted HWB’s "doctrine".

Was shown genital organs of closely allied Chrysomelidae.

Albert Günther is candidate for position at Museum.

Encloses a question [missing] concerning language [from Hensleigh Wedgwood].

Asks for news of HWB and his book.

There has been sickness in CD’s family; one of the boys [and Emma] had scarlet fever.

Has had a letter from Edwin Brown of Burton who is working on classification of Carabi.

Thanks for last note. Assures HWB that all writers have problems similar to his.

Plans to inquire at Linnean Society for HWB’s paper.

His family, including Mrs Darwin and Leonard, are now well.

Just finished HWB’s paper ["Contributions to an insect fauna of the Amazon valley", Trans. Linn. Soc. Lond. 23 (1862): 495–566], one of the most remarkable he has ever read. Found mimetic cases and connection of facts marvellous. Finds equally important the facts on variation and segregation of complete and semi-complete species. Questions whether insect mimicry is not due to small size and defencelessness. Criticises title of paper. Mentions that Wallace will appreciate it.

[Apparently in reply to question in missing portion of 3825.] A written agreement is unnecessary, but a letter stating terms would prevent misundertanding. He will attempt to have a review of HWB’s paper published.

Thanks for paper and references on variations [missing].

Regrets HWB’s trouble about artists, etc., saying such trouble is a law of nature.

Asks whether HWB has heard of starving Indians who are forced to cook in different ways, and eat new things.