Discusses a proposed expedition to Australia. Urges collecting and investigating productions of isolated islands. Recommends dredging the sea-bottom.

Mentions keeping Helix pomatia alive in sea-water.

CD returns a letter from Wollaston.

Although opposed to the Forbesian doctrine [of continental extension] as a general rule, CD would have no objection to its being proved in some cases. Does not think Wollaston has proved it; nor can anyone until more is known about the means of distribution of insects – but the identity of the two faunas is certainly interesting.

His health is very poor and his "everlasting species-Book" quite overwhelms him with work. It is beyond his powers, but he hopes to live to finish it.

Comments on letter from Georg Hartung to CL dealing with erratic boulders.

Discusses migration of plants and animals.

A letter from Thomas Thomson on heat endured by temperate plants.

No summary available.

Encloses MS by A. R. Wallace. CD has been forestalled. " . . . if Wallace had my MS sketch written out in 1842 he could not have made a better short abstract!" Wallace does not say if he wishes CD to publish MS, but CD will offer to send it to journal.

No summary available.

Everything in Wallace’s sketch also appears in CD’s sketch of 1844. A year ago CD sent a short sketch of his views to Asa Gray. Can CD honourably publish his sketch now that Wallace has sent outline of his views? "I would far rather burn my whole book than that he or any man shd. think that I had behaved in a paltry spirit." Does not believe Wallace originated his views from anything CD wrote to him.

No summary available.

Is it fair to take advantage of knowing that Wallace is in the field? Seems hard on CD to lose priority of many years, but does not feel this alters justice of case.

Baby [Charles Waring Darwin] has much fever. Frightened because three children in village have died from scarlet fever.

No summary available.

Thanks for abstract of Etna paper [Philos. Trans. R. Soc. Lond. 148 (1858): 703–86]. Never expected to see Élie de Beaumont’s theory ["craters of elevation"] so completely upset. "He must have picked out favourable cases for measurement."

More than satisfied by what was done at Linnean Society [joint reading of CD’s and Wallace’s papers: "Tendency of species to form varieties", Collected papers 2: 3–19]. Intends to prepare longer abstract.

Has heard that CL has spoken to John Murray about publication [of Origin]. Encloses prospective title-page. Asks whether he ought to tell John Murray about unorthodoxy of the book.

CD is grateful to CL for his help in arranging with Murray for publication [of Origin]. Sorry Murray objects to term "abstract" in title, but will defer to him and CL.

Discusses S. S. Haldeman’s paper ["Enumeration of the recent freshwater Mollusca", Boston J. Nat. Hist. 4 (1844): 468–84].

Centres of species origin.

Describes his corrections of Origin.

Thanks CL for copy of his paper ["Structure of lavas", Philos. Trans. R. Soc. Lond. 148 (1858): 703–86].

Promises him a copy of Origin.

CL’s research on flint tools.

Promises to send proof-sheets of Origin. Discusses his view of species.

Ill health of himself and his family.

Thanks CL for his favourable remarks to the Geological Section of the BAAS concerning the forthcoming publication of the Origin. Hopes CL will accept his view of species.

Comments on CL’s paper ["On the occurrence of works of human art in post-Pliocene deposits", Rep. BAAS 29 (1859): 93–5].

Discusses text of Origin.

Compares Eocene and modern climates.

Mentions Hooker’s view of his geographical [distribution] chapters.

Asks CL’s opinion of his statements on distribution during "glacial and preceding warmer periods".

Mentions chapters on geological record and embryology.

Is sending off last proof-sheets of Origin.

Asks CL’s opinion of final chapter. Mentions difficulties of his argument.

Is too unwell to start for Ilkley.

Murray’s printing of 1250 copies seems too large to CD.

CL’s comments on Origin. Mentions corrections to last chapter suggested by CL.

Comments on lack of peculiar bird species on Madeira and Bermuda. Emphasises importance of American types in Galapagos.

Denies necessity of continued creation of primitive "Monads".

Denies need for new powers and any principle of improvement.

Discusses gradations of intellectual powers.

Adaptive inferiority and extinction of groups of species and genera.

Asserts that climate is less important than the struggle with other organisms.

Suggests an experiment involving primroses and cowslips.

The chapter on hybridisation.

Rudimentary organs.

Gives opinion of Lamarck’s work.